4005/10 | Tocris Bioscience 4005/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4005/10

catalog :

4005/10

quantity :

10 mg (also 50 mg)

price :

111 USD

citations: 3

Reference
Chao X, Wang S, Yang L, Ni H, Ding W. Trehalose activates hepatic transcription factor EB (TFEB) but fails to ameliorate alcohol-impaired TFEB and liver injury in mice. Alcohol Clin Exp Res. 2021;45:1950-1964 pubmed publisher
Yan W, Long P, Wei D, Yan W, Zheng X, Chen G, et al. Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study. BMC Ophthalmol. 2020;20:55 pubmed publisher
Gu C, Xing Y, Jiang L, Chen M, Xu M, Yin Y, et al. Impaired cardiac SIRT1 activity by carbonyl stress contributes to aging-related ischemic intolerance. PLoS ONE. 2013;8:e74050 pubmed publisher

product information

master code :

4005

SKU :

4005/10

product name :

Alda 1

unit size :

10 mg (also 50 mg)

description :

ALDH2 activator; cardioprotective

target :

Dehydrogenase Activators

category :

Small Molecules

purity :

99%

observed molecular weight :

324.16

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Alda 1 is an activator of aldehyde dehydrogenase 2 (ALDH2). Increases activity of wild-type ALDH2*1 and variant ALDH2*2 (by ~2-fold and 11-fold respectively). Capable of partly restoring mutant ALDH2*2 activity; protective against cardiac ischemia.

top caption :

ALDH2 activator; cardioprotective

extended description :

ALDH2 activator; cardioprotective

chemical name text :

N-(1,3-Benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide

formula :

C15H11Cl2NO3

formula text :

C15H11Cl2NO3

cas num :

349438-38-6

USD :

111 USD

product details :

ALDH2 activator; cardioprotective

storage :

Store at +4░C