LDN 57444 | Tocris Bioscience 3998 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LDN 57444

catalog :

3998

quantity :

10 mg (also 50 mg)

price :

147 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zlatic S, Vrailas Mortimer A, Gokhale A, Carey L, Scott E, Burch R, et al. Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees. Cell Syst. 2018;6:368-380.e6 pubmed publisher

product information

brand :

Tocris

master code :

3998

SKU :

3998/10

product name :

LDN 57444

description :

Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor

target :

Hydrolase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

397.64

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) activity (Ki = 0.4 M). Causes cell death through the apoptosis pathway; increases levels of highly ubiquitinated proteins and decreases ubiquitin proteasome activity. Activity leads to dramatic alterations in synaptic protein distribution and spine morphology in vivo .

catalog number base :

3998

product keywords :

LDN57444 UCH L1 inhibitors inhibits ubiquitin C-terminal hydrolases UCH-L1 Deubiquitinating Enzymes 3998,

extended description :

Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor

chemical name text :

5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)

formula :

C 17 H 11 Cl 3 N 2 O 3

formula text :

C17H11Cl3N2O3

cas num :

668467-91-2

2020 USD :

144

2021 USD :

147 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage