LDN 57444 | Tocris Bioscience 3998/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LDN 57444

catalog :

3998/10

quantity :

10 mg (also 50 mg)

price :

147 USD

citations: 1

Reference
Zlatic S, Vrailas Mortimer A, Gokhale A, Carey L, Scott E, Burch R, et al. Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees. Cell Syst. 2018;6:368-380.e6 pubmed publisher

product information

brand :

Tocris

SKU :

3998/10

product name :

LDN 57444

unit sizes :

10 mg (also 50 mg)

description :

Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor

target :

Hydrolase Inhibitors

category :

Small Molecules

purity :

98%

storage :

Desiccate at +4°C

observed molecular weight :

397.64

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) activity (Ki = 0.4 M). Causes cell death through the apoptosis pathway; increases levels of highly ubiquitinated proteins and decreases ubiquitin proteasome activity. Activity leads to dramatic alterations in synaptic protein distribution and spine morphology in vivo .

catalog number base :

3998

extended description :

Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor

chemical name text :

5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)

formula :

C 17 H 11 Cl 3 N 2 O 3

formula text :

C17H11Cl3N2O3

cas num :

668467-91-2

USD :

147 USD

default size :

TRUE

product details :

Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor