product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Alexidine dihydrochloride
catalog :
3979
quantity :
50 mg
price :
117 USD
more info or order :
citations: 1
Reference
Niemi N, Lanning N, Westrate L, Mackeigan J. Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death. PLoS ONE. 2013;8:e53803 pubmed publisher
product information
brand :
Tocris
master code :
3979
SKU :
3979/50
product name :
Alexidine dihydrochloride
description :
Selective inhibitor of PTPMT1
target :
Protein Tyrosine Phosphatase Inhibitors
category :
Small Molecules
unit size :
50 mg
observed molecular weight :
581.71
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective inhibitor of protein tyrosine phosphatases localized to mitochondrion 1 (PTPMT1) (IC50 = 1.08 M in vitro ). Stimulates increased insulin secretion by -cells in rat pancreatic islets. Displays antitcancer properties in FaDu cells. Also preserves functional hematopoietic stem cells ex vivo .
catalog number base :
3979
product keywords :
protein tyrosine phosphatases PTP localized localised to mitochondrion 1 PTPMT1 inhibitors inhibits stem cells Protein Tyrosine Phosphatases Stem Cell Signaling 3979,
extended description :
Selective inhibitor of PTPMT1
chemical name text :
N,N -Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide dihydrochloride
formula :
C 26 H 56 N 10 .2HCl
formula text :
C26H56N10.2HCl
cas num :
1715-30-6
2020 USD :
113
2021 USD :
117 USD
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK