3979/50 | Tocris Bioscience 3979/50 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

3979/50

catalog :

3979/50

quantity :

50 mg

price :

148 USD

citations: 1

Reference
Niemi N, Lanning N, Westrate L, Mackeigan J. Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death. PLoS ONE. 2013;8:e53803 pubmed publisher

product information

master code :

3979

SKU :

3979/50

product name :

Alexidine dihydrochloride

unit size :

50 mg

description :

Selective inhibitor of PTPMT1

target :

Protein Tyrosine Phosphatase Inhibitors

category :

Small Molecules

observed molecular weight :

581.71

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Alexidine dihydrochloride is a selective inhibitor of protein tyrosine phosphatases localized to mitochondrion 1 (PTPMT1) (IC50 = 1.08 M in vitro ). Stimulates increased insulin secretion by -cells in rat pancreatic islets. Displays antitcancer properties in FaDu cells. Also preserves functional hematopoietic stem cells ex vivo .

top caption :

Selective inhibitor of PTPMT1

extended description :

Selective inhibitor of PTPMT1

chemical name text :

N,N -Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide dihydrochloride

formula :

C26H56N10.2HCl

formula text :

C26H56N10.2HCl

cas num :

1715-30-6

USD :

148 USD

product details :

Selective inhibitor of PTPMT1

storage :

Desiccate at -20░C