3-Methyladenine | Tocris Bioscience 3977/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

3-Methyladenine

catalog :

3977/50

quantity :

50 mg

price :

138 USD

more info or order :

Tocris Bioscience product webpage

citations: 8

Reference
Park G, Jeong J, Kim D. Gliotoxin Enhances Autophagic Cell Death via the DAPK1-TAp63 Signaling Pathway in Paclitaxel-Resistant Ovarian Cancer Cells. Mar Drugs. 2019;17: pubmed publisher
Perez Vidakovics M, Ure A, Arrías P, Romanowski V, Gomez R. Junín virus induces autophagy in human A549 cells. PLoS ONE. 2019;14:e0218730 pubmed publisher
Sagrillo Fagundes L, Bienvenue Pariseault J, Vaillancourt C. Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells. PLoS ONE. 2019;14:e0202458 pubmed publisher
Hylin M, Zhao J, Tangavelou K, Rozas N, Hood K, MacGowan J, et al. A role for autophagy in long-term spatial memory formation in male rodents. J Neurosci Res. 2017;: pubmed publisher
Nepal S, Kim M, Hong J, Kim S, Sohn D, Lee S, et al. Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: involvement of p53/FoxO3A axis. Oncotarget. 2015;6:7166-81 pubmed
Wolf E, Gebhardt A, Kawauchi D, Walz S, von Eyss B, Wagner N, et al. Miz1 is required to maintain autophagic flux. Nat Commun. 2013;4:2535 pubmed publisher
Wang H, Wu C, Cheng T, Kuo C, Tsai Y, Chiang S, et al. Active Constituents from Liriope platyphylla Root against Cancer Growth In Vitro. Evid Based Complement Alternat Med. 2013;2013:857929 pubmed publisher
Kim H, Montana V, Jang H, Parpura V, Kim J. Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: a potential role for reducing lipid accumulation. J Biol Chem. 2013;288:22693-705 pubmed publisher

product information

brand :

Tocris

master code :

3977

SKU :

3977/50

rank :

0.061

product name :

3-Methyladenine

description :

Class III PI 3-kinase inhibitor; also inhibits autophagy

target :

PI 3-Kinase Inhibitors

category :

Small Molecules

sizes available :

50 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

3-Methyladenine is an inhibitor of class III phosphatidylinositol 3-kinase (PI 3-kinase); also inhibits the autophagic sequestration of cell proteins in rat hepatocytes. Blocks apoptosis in cerebellar granule cells (CGCs) following serum and potassium deprivation.

extended description :

Class III PI 3-kinase inhibitor; also inhibits autophagy

chemical name text :

3-Methyl-3H-purin-6-amine

formula :

C 6 H 7 N 5

formula text :

C6H7N5

cas num :

5142-23-4

USD :

138 USD

product details :

Class III PI 3-kinase inhibitor; also inhibits autophagy

alt names :

3-MA

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage