This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
3976/1
catalog :
3976/1
quantity :
1 mg
price :
141 USD
citations: 2
Reference
Csikós V, Varro P, Bódi V, Oláh S, Vilagi I, Dobolyi A. The mycotoxin deoxynivalenol activates GABAergic neurons in the reward system and inhibits feeding and maternal behaviours. Arch Toxicol. 2020;94:3297-3313 pubmed publisher
Bae H, Pestka J. Deoxynivalenol induces p38 interaction with the ribosome in monocytes and macrophages. Toxicol Sci. 2008;105:59-66 pubmed publisher
product information
master code :
3976
SKU :
3976/1
product name :
Deoxynivalenol
unit size :
1 mg
description :
Mycotoxin; potent protein synthesis inhibitor
target :
Miscellaneous Compounds
category :
Small Molecules
purity :
98%
observed molecular weight :
296.32
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Exhibits cytotoxic activity in vivo via the ribotoxic stress response. Induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF- B into the nucleus.
top caption :
Mycotoxin; potent protein synthesis inhibitor
extended description :
Mycotoxin; potent protein synthesis inhibitor
chemical name text :
3 ,7 ,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one
formula :
C15H20O6
formula text :
C15H20O6
cas num :
51481-10-8
USD :
141 USD
product details :
Mycotoxin; potent protein synthesis inhibitor
alt names :
DON,Vomitoxin
storage :
Store at +4░C
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK