Latrunculin A | Tocris Bioscience 3973/100U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Latrunculin A

catalog :

3973/100U

quantity :

100 ug

price :

222 USD

more info or order :

Tocris Bioscience product webpage

citations: 19

Reference
Tazerart S, Mitchell D, Miranda Rottmann S, Araya R. A spike-timing-dependent plasticity rule for dendritic spines. Nat Commun. 2020;11:4276 pubmed publisher
Lionarons D, Hancock D, Rana S, East P, Moore C, Murillo M, et al. RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance. Cancer Cell. 2019;: pubmed publisher
Lim S, Hermance N, Mudianto T, Mustaly H, Mauricio I, Vittoria M, et al. Identification of the kinase STK25 as an upstream activator of LATS signaling. Nat Commun. 2019;10:1547 pubmed publisher
Wisdom K, Adebowale K, Chang J, Lee J, Nam S, Desai R, et al. Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments. Nat Commun. 2018;9:4144 pubmed publisher
Haag N, Schüler S, Nietzsche S, Hübner C, Strenzke N, Qualmann B, et al. The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea. Cell Rep. 2018;24:2418-2431.e6 pubmed publisher
Davies T, Kim H, Romano Spica N, Lesea Pringle B, Dumont J, Shirasu Hiza M, et al. Cell-intrinsic and -extrinsic mechanisms promote cell-type-specific cytokinetic diversity. elife. 2018;7: pubmed publisher
Neumann N, Perrone M, Veldhuis J, Huebner R, Zhan H, Devreotes P, et al. Coordination of Receptor Tyrosine Kinase Signaling and Interfacial Tension Dynamics Drives Radial Intercalation and Tube Elongation. Dev Cell. 2018;45:67-82.e6 pubmed publisher
Lettau M, Armbrust F, Dohmen K, Drews L, Poch T, Dietz M, et al. Mechanistic peculiarities of activation-induced mobilization of cytotoxic effector proteins in human T cells. Int Immunol. 2018;30:215-228 pubmed publisher
Hubaud A, Regev I, Mahadevan L, Pourquie O. Excitable Dynamics and Yap-Dependent Mechanical Cues Drive the Segmentation Clock. Cell. 2017;171:668-682.e11 pubmed publisher
Han C, Juncadella I, Kinchen J, Buckley M, Klibanov A, Dryden K, et al. Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation. Nature. 2016;539:570-574 pubmed publisher
Petrosyan A, Casey C, Cheng P. The role of Rab6a and phosphorylation of non-muscle myosin IIA tailpiece in alcohol-induced Golgi disorganization. Sci Rep. 2016;6:31962 pubmed publisher
Koopmans T, Kumawat K, Halayko A, Gosens R. Regulation of actin dynamics by WNT-5A: implications for human airway smooth muscle contraction. Sci Rep. 2016;6:30676 pubmed publisher
Suzuki R, Hotta K, Oka K. Spatiotemporal quantification of subcellular ATP levels in a single HeLa cell during changes in morphology. Sci Rep. 2015;5:16874 pubmed publisher
Araki Y, Zeng M, Zhang M, Huganir R. Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP. Neuron. 2015;85:173-89 pubmed publisher
Heidary Arash E, Song K, Song S, Shiban A, Attisano L. Arhgef7 promotes activation of the Hippo pathway core kinase Lats. EMBO J. 2014;33:2997-3011 pubmed publisher
Saba T, Chung Y, Hong J, Sajjan U, Bentley J, Hershenson M. Rhinovirus-induced macrophage cytokine expression does not require endocytosis or replication. Am J Respir Cell Mol Biol. 2014;50:974-84 pubmed publisher
Oenema T, Maarsingh H, Smit M, Groothuis G, Meurs H, Gosens R. Bronchoconstriction Induces TGF-? Release and Airway Remodelling in Guinea Pig Lung Slices. PLoS ONE. 2013;8:e65580 pubmed publisher
Dalton C, Carroll J. Biased inheritance of mitochondria during asymmetric cell division in the mouse oocyte. J Cell Sci. 2013;126:2955-64 pubmed publisher
Kawashima S, Takemoto A, Nurse P, Kapoor T. Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology. Chem Biol. 2012;19:893-901 pubmed publisher

product information

brand :

Tocris

master code :

3973

SKU :

3973/100U

rank :

0.061

product name :

Latrunculin A

description :

Inhibitor of actin assembly and polymerization

target :

Actin-related Products

category :

Small Molecules

sizes available :

100 ug

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Latrunculin A is a reversible inhibitor of actin assembly; blocks actin adenine nucleotide exchange. Complexes with actin in vitro and interacts with actin monomers only, unlike cytochalasins. Prevents actin repolymerization into filaments and disrupts the actin cytoskeleton. . This product is typically reconstituted in DMSO as a primary solvent.

extended description :

Inhibitor of actin assembly and polymerization

chemical name text :

4-[(1R,4Z,8E,10Z,12S,15R, 17R)-17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone

formula :

C 22 H 31 NO 5 S

formula text :

C22H31NO5S

cas num :

76343-93-6

USD :

222 USD

product details :

Inhibitor of actin assembly and polymerization

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage