AR-A 014418 | Tocris Bioscience 3966 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AR-A 014418

catalog :

3966

quantity :

10 mg (also 50 mg)

price :

193 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Cuesto G, Jordán Álvarez S, Enriquez Barreto L, Ferrús A, Morales M, Acebes A. GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons. PLoS ONE. 2015;10:e0118475 pubmed publisher
Penas C, Mishra J, Wood S, SchÃ¼rer S, Roush W, Ayad N. GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation. Cell Cycle. 2015;14:417-24 pubmed publisher
Chen M, Maloney J, Kallop D, Atwal J, Tam S, Baer K, et al. Spatially coordinated kinase signaling regulates local axon degeneration. J Neurosci. 2012;32:13439-53 pubmed

product information

brand :

Tocris

master code :

3966

SKU :

3966/10

product name :

AR-A 014418

description :

Selective GSK-3 inhibitor

target :

GSK-3 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

308.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are 100 M) and over 26 other kinases. Inhibits -amyloid-mediated neurodegeneration in hippocampal slices.

catalog number base :

3966

product keywords :

ARA014418 glycogen synthase kinase 3 GSK-3 GSK3 inhibitors inhibits Glycogen Synthase Kinase 3 Glycogen Synthase Kinase 3966,

extended description :

Selective GSK-3 inhibitor

chemical name text :

N-[(4-Methoxyphenyl)methyl]-N -(5-nitro-2-thiazolyl)urea

formula :

C 12 H 12 N 4 O 4 S

formula text :

C12H12N4O4S

cas num :

487021-52-3

2020 USD :

185

2021 USD :

193 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage