AR-A 014418 | Tocris Bioscience 3966/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AR-A 014418

catalog :

3966/10

quantity :

10 mg (also 50 mg)

price :

224 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Cuesto G, Jordán Álvarez S, Enriquez Barreto L, Ferrús A, Morales M, Acebes A. GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons. PLoS ONE. 2015;10:e0118475 pubmed publisher
Penas C, Mishra J, Wood S, SchÃ¼rer S, Roush W, Ayad N. GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation. Cell Cycle. 2015;14:417-24 pubmed publisher
Chen M, Maloney J, Kallop D, Atwal J, Tam S, Baer K, et al. Spatially coordinated kinase signaling regulates local axon degeneration. J Neurosci. 2012;32:13439-53 pubmed

image

image 1 :

Cat.No. 3966 - AR-A 014418 C12H12N4O4S CAS No. 487021-52-3

product information

brand :

Tocris

master code :

3966

SKU :

3966/10

rank :

0.061

product name :

AR-A 014418

description :

Selective GSK-3 inhibitor

target :

GSK-3 Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are 100 M) and over 26 other kinases. Inhibits -amyloid-mediated neurodegeneration in hippocampal slices.

extended description :

Selective GSK-3 inhibitor

chemical name text :

N-[(4-Methoxyphenyl)methyl]-N -(5-nitro-2-thiazolyl)urea

formula :

C 12 H 12 N 4 O 4 S

formula text :

C12H12N4O4S

cas num :

487021-52-3

USD :

224 USD

product details :

Selective GSK-3 inhibitor

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage