GSK 3787 | Tocris Bioscience 3961/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 3787

catalog :

3961/10

quantity :

10 mg (also 50 mg)

price :

234 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Yuan B, Shi K, Zha J, Cai Y, Gu Y, Huang K, et al. Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway. Cell Death Dis. 2023;14:51 pubmed publisher
Busato S, Ford H, Abdelatty A, Estill C, Bionaz M. Peroxisome Proliferator-Activated Receptor Activation in Precision-Cut Bovine Liver Slices Reveals Novel Putative PPAR Targets in Periparturient Dairy Cows. Front Vet Sci. 2022;9:931264 pubmed publisher
Busato S, Bionaz M. The interplay between non-esterified fatty acids and bovine peroxisome proliferator-activated receptors: results of an in vitro hybrid approach. J Anim Sci Biotechnol. 2020;11:91 pubmed publisher
Samokhvalov V, Zlobine I, Jamieson K, Jurasz P, Chen C, Lee K, et al. PPARÎ´ signaling mediates the cytotoxicity of DHA in H9c2 cells. Toxicol Lett. 2015;232:10-20 pubmed publisher
Myojo M, Nagata D, Fujita D, Kiyosue A, Takahashi M, Satonaka H, et al. Telmisartan activates endothelial nitric oxide synthase via Ser1177 phosphorylation in vascular endothelial cells. PLoS ONE. 2014;9:e96948 pubmed publisher

image

image 1 :

Cat.No. 3961 - GSK 3787 C15H12ClF3N2O3S CAS No. 188591-46-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3961

SKU :

3961/10

product name :

GSK 3787

description :

Potent and selective PPAR antagonist

target :

PPAR delta Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

392.78

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GSK 3787 is a potent and selective peroxisome proliferator-activated receptor (PPAR ) antagonist (pIC50 = 6.6). Displays no measurable affinity for PPAR or PPAR in vitro (pIC50< 5).

product keywords :

GSK3787 peroxisome proliferator-activated receptor PPARd PPARdelta PPAR antagonists PPARdelta Receptors 3961,

extended description :

Potent and selective PPAR antagonist

chemical name text :

4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide

formula :

C15H12ClF3N2O3S

formula text :

C15H12ClF3N2O3S

cas num :

188591-46-0

USD :

227

USD 2025 :

234 USD

product details :

Potent and selective PPAR antagonist

more info or order :

Tocris Bioscience product webpage