trans-Ned 19 | Tocris Bioscience 3954/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

trans-Ned 19

catalog :

3954/10

quantity :

10 mg

price :

388 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Joe Y, Chen Y, Park J, Kim H, Rah S, Ryu J, et al. Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis. Cell Rep. 2020;30:1063-1076.e5 pubmed publisher
Favia A, Pafumi I, Desideri M, Padula F, Montesano C, Passeri D, et al. NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis. Sci Rep. 2016;6:18925 pubmed publisher

product information

brand :

Tocris

master code :

3954

SKU :

3954/10

rank :

0.061

product name :

trans-Ned 19

description :

Fluorescently labels NAADP receptors in intact cells; inhibits Ca2+ release

target :

Calcium Signaling Agents

category :

Small Molecules

sizes available :

10 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

trans -Ned 19 is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM); also inhibits [32P]NAADP binding (IC50 = 0.4 nM). Fluorescently labels NAADP receptors in intact cells. Stereosiomer of cis -Ned 19 (Cat. No. 3953).

extended description :

Fluorescently labels NAADP receptors in intact cells; inhibits Ca2+ release

chemical name text :

(1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid

formula :

C 30 H 31 FN 4 O 3

formula text :

C30H31FN4O3

cas num :

1354235-96-3

USD :

388 USD

product details :

Fluorescently labels NAADP receptors in intact cells; inhibits Ca2+ release

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage