product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CK 666
catalog :
3950/10
quantity :
10 mg (also 50 mg)
price :
227 USD
more info or order :
citations: 14
Reference
Roesler M, Lombino F, Freitag S, Schweizer M, Hermans Borgmeyer I, Schwarz J, et al. Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization. Front Cell Neurosci. 2019;13:330 pubmed publisher
Tabdanov E, Puram V, Win Z, Alamgir A, Alford P, Provenzano P. Bimodal sensing of guidance cues in mechanically distinct microenvironments. Nat Commun. 2018;9:4891 pubmed publisher
Tabdanov E, Puram V, Zhovmer A, Provenzano P. Microtubule-Actomyosin Mechanical Cooperation during Contact Guidance Sensing. Cell Rep. 2018;25:328-338.e5 pubmed publisher
Sepúlveda Ramírez S, Toledo Jacobo L, Henson J, Shuster C. Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo. Dev Biol. 2018;437:140-151 pubmed publisher
Yamagishi Y, Oya K, Matsuura A, Abe H. Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo. Biochem Biophys Res Commun. 2018;496:834-839 pubmed publisher
Logue J, Cartagena Rivera A, Chadwick R. c-Src activity is differentially required by cancer cell motility modes. Oncogene. 2018;37:2104-2121 pubmed publisher
Bharadwaj M, Strohmeyer N, Colo G, Helenius J, Beerenwinkel N, Schiller H, et al. αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin. Nat Commun. 2017;8:14348 pubmed publisher
Basu S, Kustanovich I, Lamprecht R. Arp2/3 and VASP Are Essential for Fear Memory Formation in Lateral Amygdala. Eneuro. 2016;3: pubmed
Han C, Juncadella I, Kinchen J, Buckley M, Klibanov A, Dryden K, et al. Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation. Nature. 2016;539:570-574 pubmed publisher
Panousopoulou E, Hobbs C, Mason I, Green J, Formstone C. Epiboly generates the epidermal basal monolayer and spreads the nascent mammalian skin to enclose the embryonic body. J Cell Sci. 2016;129:1915-27 pubmed publisher
Sorce B, Escobedo C, Toyoda Y, Stewart M, Cattin C, Newton R, et al. Mitotic cells contract actomyosin cortex and generate pressure to round against or escape epithelial confinement. Nat Commun. 2015;6:8872 pubmed publisher
Moreau H, Lemaître F, Garrod K, Garcia Z, Lennon Duménil A, Bousso P. Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest. Proc Natl Acad Sci U S A. 2015;112:12151-6 pubmed publisher
Tornavaca O, Chia M, Dufton N, Almagro L, Conway D, Randi A, et al. ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation. J Cell Biol. 2015;208:821-38 pubmed publisher
Dalton C, Carroll J. Biased inheritance of mitochondria during asymmetric cell division in the mouse oocyte. J Cell Sci. 2013;126:2955-64 pubmed publisher
product information
brand :
Tocris
master code :
3950
SKU :
3950/10
rank :
0.061
product name :
CK 666
description :
Arp2/3 inhibitor; inhibits actin polymerization
target :
Actin-related Products
category :
Small Molecules
sizes available :
10 mg (also 50 mg)
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CK 666 is an inhibitor of the Arp2/3 complex; inhibits actin polymerization (IC50 = 4 M).
extended description :
Arp2/3 inhibitor; inhibits actin polymerization
chemical name text :
2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
formula :
C 18 H 17 FN 2 O
formula text :
C18H17FN2O
cas num :
442633-00-3
USD :
227 USD
product details :
Arp2/3 inhibitor; inhibits actin polymerization
storage :
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK