TNP | Tocris Bioscience 3946/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TNP

catalog :

3946/10

quantity :

10 mg

price :

267 USD

citations: 1

Reference
Daryadel A, Haykir B, K xfc ng C, Bugarski M, Bettoni C, Schnitzbauer U, et al. Acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals. Acta Physiol (Oxf). 2022;235:e13815 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3946

SKU :

3946/10

product name :

TNP

description :

Inhibitor of IP6K; also inhibits IP3K

target :

Other Kinase Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

97%

storage :

Store at +4°C

observed molecular weight :

443.38

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TNP is a reversible inositol hexakisphosphate kinase (IP6K) inhibitor (IC50 = 0.47 M for inhibition of InsP7 formation). Also inhibits inositol 1,4,5-trisphosphate 3-kinase (IP3K) (IC50 = 10.2 M). Binds to the ATP binding site of IP3K (Ki = 4.3 M).

product keywords :

TNP inhibitors inhibits inositol 1,4,5-triphosphate 3-kinase IP3K hexakisphosphate kinases IP6K lipids Other Kinases Inositol Lipids 3946,

extended description :

Inhibitor of IP6K; also inhibits IP3K

chemical name text :

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine

formula :

C20H16F3N7O2

formula text :

C20H16F3N7O2

cas num :

519178-28-0

USD :

264

USD 2025 :

267 USD

product details :

Inhibitor of IP6K; also inhibits IP3K