Colivelin | Tocris Bioscience 3945 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Colivelin

catalog :

3945

quantity :

500 ug

price :

314 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Vergani A, Tezza S, D Addio F, Fotino C, Liu K, Niewczas M, et al. Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7. Circulation. 2013;127:463-75 pubmed publisher

product information

brand :

Tocris

master code :

3945

SKU :

3945/500U

product name :

Colivelin

description :

STAT3 activator; also protects against -amyloid neurotoxicity

target :

Amyloid beta Peptides

category :

Peptides

unit size :

500 ug

observed molecular weight :

2645.13

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Neuroprotective peptide and activator of STAT3. Protects neurons against the neurotoxic effects of amyloid -peptide (1-43) at a concentration of 100 fM in vitro . Suppresses neuronal death by activating STAT3 in vitro ; upregulates cholinergic transmission and ameliorates memory impairment in Alzheimer s disease (AD) models. Also prevents alcohol-induced apoptosis in a fetal mouse model. Brain penetrant.

catalog number base :

3945

product keywords :

neuroprotectant neuroprotective beta-amyloid b-amyloid -amyloid alzheimers disease STAT3 amyloidbeta amyloidb amyloid Amyloid Beta Peptides STAT 3945,

extended description :

STAT3 activator; also protects against -amyloid neurotoxicity

formula :

C 119 H 206 N 32 O 35

formula text :

C119H206N32O35

cas num :

867021-83-8

2020 USD :

307

2021 USD :

314 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage