XCT 790 | Tocris Bioscience 3928 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

XCT 790

catalog :

3928

quantity :

10 mg (also 50 mg)

price :

193 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Hwang J, Purdy J, Wu K, Rabinowitz J, Shenk T. Estrogen-related receptor Î± is required for efficient human cytomegalovirus replication. Proc Natl Acad Sci U S A. 2014;111:E5706-15 pubmed publisher
Teng C, BEAMES B, Alex Merrick B, Martin N, Romeo C, Jetten A. Development of a stable cell line with an intact PGC-1Î±/ERRÎ± axis for screening environmental chemicals. Biochem Biophys Res Commun. 2014;444:177-81 pubmed publisher

product information

brand :

Tocris

master code :

3928

SKU :

3928/10

product name :

XCT 790

description :

Selective ERR inverse agonist

target :

Estrogen and Related Receptor Inverse Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

596.42

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective ERR inverse agonist (IC50 = ~400 nM). Displays no antagonist activity at ERR or ER at concentrations below 10 M. Interferes with PPAR coactivator-1 (PGC-1 )/ERR -dependent signaling: inhibits PGC-1 induction of ERR and MAO-B gene expression and downregulates the constitutive transcriptional activity of ERR in numerous cell lines.

catalog number base :

3928

product keywords :

XCT790 ERRalpha ERRa ERR antagonists inverse agonists PPAR PPARg PPARgamma coactivator-1 coactivator-1alpha coactivator-1a PGC-1 PGC-1alpha PGC-1a signaling signalling Estrogen and Related Receptors 3928,

extended description :

Selective ERR inverse agonist

chemical name text :

3-[4-(2,4-Bis-trifluoromethylbenzyloxy)-3-methoxyphenyl]-2-cyano-N-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)acrylamide

formula :

C 23 H 13 F 9 N 4 O 3 S

formula text :

C23H13F9N4O3S

cas num :

725247-18-7

2020 USD :

185

2021 USD :

193 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage