AMG 548 | Tocris Bioscience 3920 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AMG 548

catalog :

3920

quantity :

10 mg

price :

289 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Eckle T, Brodsky K, Bonney M, Packard T, Han J, Borchers C, et al. HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium. PLoS Biol. 2013;11:e1001665 pubmed publisher

product information

brand :

Tocris

master code :

3920

SKU :

3920/10

product name :

AMG 548

description :

Potent and selective p38 inhibitor

target :

p38 Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

461.56

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective inhibitor of p38 (Ki values are 0.5, 3.6, 2600 and 4100 nM for p38 , p38 , p38 and p38 respectively). Displays 1000-fold selectivity against 36 other kinases; inhibits whole blood LPS-stimulated TNF (IC50 = 3 nM). Efficacious in acute and chronic models of arthritis.

catalog number base :

3920

product keywords :

AMG548 potent selective p38alpha p38a p38 inhibitors inhibits p38 3920,

extended description :

Potent and selective p38 inhibitor

chemical name text :

2-[[(2S)-2-Amino-3-phenylpropyl]amino]-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-4(3H)-pyrimidinone

formula :

C 29 H 27 N 5 O

formula text :

C29H27N5O

cas num :

864249-60-5

2020 USD :

280

2021 USD :

289 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage