product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Pyrimethamine
catalog :
3918
quantity :
50 mg
price :
73 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
3918
SKU :
3918/50
product name :
Pyrimethamine
description :
Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor
target :
Multidrug Transporter Inhibitors
category :
Small Molecules
unit size :
50 mg
purity :
99%
observed molecular weight :
248.71
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent inhibitor of multidrug and toxin extrusion (MATE) transporters (Ki values are 46 and 77 nM for human MATE2-K-HEK293 and MATE1-HEK293 cells respectively). Also inhibits dihydrofolate reductase (DHFR) and STAT3. Decreases proliferation of human autosomal dominant polycystic kidney disease cells.
catalog number base :
3918
product keywords :
inhibitors inhibits multidrug and toxin extrusion MATE transporters dihydrofolate reductase DHFR STAT3 signal transducer and activator of transcription 3 Multidrug Transporters Dihydrofolate Reductase STAT 3918,
extended description :
Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor
chemical name text :
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
formula :
C 12 H 13 ClN 4
formula text :
C12H13ClN4
cas num :
58-14-0
2020 USD :
71
2021 USD :
73 USD
storage :
Store at RT
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK