Pyrimethamine | Tocris Bioscience 3918/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Pyrimethamine

catalog :

3918/50

quantity :

50 mg

price :

86 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 3918 - Pyrimethamine C12H13ClN4 CAS No. 58-14-0

product information

brand :

Tocris

master code :

3918

SKU :

3918/50

rank :

0.061

product name :

Pyrimethamine

description :

Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor

target :

Multidrug Transporter Inhibitors

category :

Small Molecules

sizes available :

50 mg

url print :

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details of functionality :

Pyrimethamine is a potent inhibitor of multidrug and toxin extrusion (MATE) transporters (Ki values are 46 and 77 nM for human MATE2-K-HEK293 and MATE1-HEK293 cells respectively). Also inhibits dihydrofolate reductase (DHFR) and STAT3. Decreases proliferation of human autosomal dominant polycystic kidney disease cells.

extended description :

Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor

chemical name text :

5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine

formula :

C 12 H 13 ClN 4

formula text :

C12H13ClN4

cas num :

58-14-0

USD :

86 USD

product details :

Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage