A 419259 trihydrochloride | Tocris Bioscience 3914 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

A 419259 trihydrochloride

catalog :

3914

quantity :

10 mg

price :

331 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Li R, Zhong C, Yu Y, Liu H, Sakurai M, Yu L, et al. Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Cell. 2019;179:687-702.e18 pubmed publisher
Gao X, Nowak Imialek M, Chen X, Chen D, Herrmann D, Ruan D, et al. Establishment of porcine and human expanded potential stem cells. Nat Cell Biol. 2019;21:687-699 pubmed publisher

product information

brand :

Tocris

master code :

3914

SKU :

3914/10

product name :

A 419259 trihydrochloride

description :

Inhibitor of Src family kinases

target :

Src Family Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

592.01

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent Hck inhibitor (IC50 = 0.43 nM). Also inhibits other Src family kinases (SFKs). Suppresses proliferation and induces apoptosis in CML cell lines including CD34+. Also inhibits acute myeloid leukemia (AML) stem cell proliferation in vitro and in vivo .

catalog number base :

3914

product keywords :

A419259 Src family kinase SFK inhibitors inhibits apoptosis inducers A419259 trihydrochloride 3HCl Src Kinases 3914,

extended description :

Inhibitor of Src family kinases

chemical name text :

7-[trans-4-(4-Methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-Pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride

formula :

C 29 H 34 N 6 O.3HCl

formula text :

C29H34N6O.3HCl

cas num :

1435934-25-0

2020 USD :

318

2021 USD :

331 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage