BIO 1211 | Tocris Bioscience 3910/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BIO 1211

catalog :

3910/1

quantity :

1 mg

price :

239 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Horwacik I, Rokita H. Modulation of interactions of neuroblastoma cell lines with extracellular matrix proteins affects their sensitivity to treatment with the anti-GD2 ganglioside antibody 14G2a. Int J Oncol. 2017;50:1899-1914 pubmed publisher
Chen W, Cao Z, Sugaya S, Lopez M, Sendra V, Laver N, et al. Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3. Nat Commun. 2016;7:11302 pubmed publisher
Lujan E, Zunder E, Ng Y, Goronzy I, Nolan G, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 2015;521:352-6 pubmed publisher
Fujita M, Takada Y, Izumiya Y, Takada Y. The binding of monomeric C-reactive protein (mCRP) to Integrins ?v?3 and ?4?1 is related to its pro-inflammatory action. PLoS ONE. 2014;9:e93738 pubmed publisher
Kota D, Dicarlo B, Hetz R, Smith P, Cox C, Olson S. Differential MSC activation leads to distinct mononuclear leukocyte binding mechanisms. Sci Rep. 2014;4:4565 pubmed publisher

image

image 1 :

Cat.No. 3910 - BIO 1211 MPUPA-Leu-Asp-Val-Pro (MPUPA = o-methylphenylureaphenylacetyl) CAS No. 187735-94-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3910

SKU :

3910/1

product name :

BIO 1211

description :

Selective 4 1 (VLA-4) inhibitor

target :

Integrin Receptor Inhibitors

unit size :

1 mg

category :

Peptides

purity :

95%

storage :

Store at -20°C

observed molecular weight :

708.8

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

BIO 1211 is a selective, high affinity 4 1 (Very Late Antigen 4; VLA-4) inhibitor; displays 200-fold selectivity for the activated form of 4 1 (KD = 70 pM; IC50 = 0.004 M). Selective for 4 1 over a range of other integrins (IC50 100 M for 1 1, 5 1 and 6 1).

product keywords :

Selective high affinity 4 1 a4b1 alpha4beta1 very late antigen VLA-4 VLA4 inhibitors inhibits integrins BIO1211 Integrins Cell Adhesion Molecules 3910,

extended description :

Selective 4 1 (VLA-4) inhibitor

formula :

C36H48N6O9

formula text :

C36H48N6O9

cas num :

187735-94-0

USD :

229

USD 2025 :

239 USD

product details :

Selective 4 1 (VLA-4) inhibitor

more info or order :

Tocris Bioscience product webpage