Toceranib | Tocris Bioscience 3909 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Toceranib

catalog :

3909

quantity :

10 mg (also 50 mg)

price :

217 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3909

SKU :

3909/10

product name :

Toceranib

description :

Potent PDGFR and VEGFR inhibitor

target :

PDGF Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

396.46

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent ATP-competitive PDGFR and VEGFR inhibitor (Ki = 5 and 6 nM, respectively); inhibits phosphorylation of c-Kit and suppresses the growth of mast cell lines expressing mutant Kit, inducing cell cycle arrest and apoptosis. Also inhibits FGFR1 (Ki = 0.5 M). Effective in vivo .

catalog number base :

3909

product keywords :

Potent PDGFR VEGFR inhibitors inhibits c-kit FGFR1 mast cell cycle arrest apoptosis tumors tumours Palladia PDGFR VEGFR Cell Cycle Inhibitors Apoptosis Inducers 3909,

extended description :

Potent PDGFR and VEGFR inhibitor

chemical name text :

5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide

formula :

C 22 H 25 FN 4 O 2

formula text :

C22H25FN4O2

cas num :

356068-94-5

2020 USD :

212

2021 USD :

217 USD

alt names :

Palladia

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage