27-Hydroxycholesterol | Tocris Bioscience 3907 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

27-Hydroxycholesterol

catalog :

3907

quantity :

10 mg

price :

320 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Schommer J, Marwarha G, Schommer T, Flick T, Lund J, Ghribi O. 27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons. BMC Neurosci. 2018;19:17 pubmed publisher
Gibson D, Collins F, Cousins F, Esnal Zufiaurre A, Saunders P. The impact of 27-hydroxycholesterol on endometrial cancer proliferation. Endocr Relat Cancer. 2018;25:381-391 pubmed publisher

product information

brand :

Tocris

master code :

3907

SKU :

3907/10

product name :

27-Hydroxycholesterol

description :

LXR agonist; also ER partial agonist

target :

LXR-like Receptor Agonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

402.65

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Liver X receptor (LXR) agonist. Also estrogen receptor partial agonist. Suppresses -estradiol -mediated breast cancer cell proliferation in vitro . Also increases -synuclein levels and induces apoptosis in human neuroblastoma cells in vitro . Endogenous cholesterol metabolite.

catalog number base :

3907

product keywords :

27OHC 27HC liver-x receptors agonists estrogen partial SERM selective modulators cholesterol 27 OHC 27 HC LXR-like Receptors Estrogen and Related Receptors 3907,

extended description :

LXR agonist; also ER partial agonist

chemical name text :

(3 ,25R)-Cholest-5-ene-3,26-diol

formula :

C 27 H 46 O 2

formula text :

C27H46O2

cas num :

20380-11-4

2020 USD :

307

2021 USD :

320 USD

alt names :

27 OHC, 27 HC

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage