NAADP tetrasodium salt | Tocris Bioscience 3905 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NAADP tetrasodium salt

catalog :

3905

quantity :

10 mg

price :

325 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Hadi T, Boytard L, Silvestro M, Alebrahim D, Jacob S, Feinstein J, et al. Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells. Nat Commun. 2018;9:5022 pubmed publisher
Ruas M, Davis L, Chen C, Morgan A, Chuang K, Walseth T, et al. Expression of CaÂ²âº-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells. EMBO J. 2015;34:1743-58 pubmed publisher
Wang X, Zhang X, Dong X, Samie M, Li X, Cheng X, et al. TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes. Cell. 2012;151:372-83 pubmed publisher
Calcraft P, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, et al. NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature. 2009;459:596-600 pubmed publisher

product information

brand :

Tocris

master code :

3905

SKU :

3905/10

product name :

NAADP tetrasodium salt

description :

Ca2+ mobilizing agent

target :

Ryanodine Receptor Modulators

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

832.32

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ca2+ mobilizing agent. Initiates Ca2+ release via type 1 ryanodine receptor (RyR1) activation. Also regulates Ca2+ release from intracellular stores distinct from the endoplasmic reticulum (ER); displays affinity for two-pore channels (TPCs) which release Ca2+ from acidic organelles.

catalog number base :

3905

product keywords :

general Calcium Signaling Signalling Agents Ca2+ mobilization beta-NAADP -NAADP ryanodine receptors 5502-96-5 beta-NAADP General Calcium Signaling Agents Ryanodine Receptors 3905, Ryanodine receptors, RyRs, RyR

extended description :

Ca2+ mobilizing agent

chemical name text :

Nicotinic acid adenine dinucleotide phosphate tetrasodium salt

formula :

C 21 H 23 N 6 Na 4 O 18 P 3

formula text :

C21H23N6Na4O18P3

2020 USD :

315

2021 USD :

325 USD

alt names :

NAADP

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage