JNJ 303 | Tocris Bioscience 3899 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 303

catalog :

3899

quantity :

10 mg (also 50 mg)

price :

191 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Björk S, Ojala E, Nordström T, Ahola A, Liljeström M, Hyttinen J, et al. Evaluation of Optogenetic Electrophysiology Tools in Human Stem Cell-Derived Cardiomyocytes. Front Physiol. 2017;8:884 pubmed publisher

product information

brand :

Tocris

master code :

3899

SKU :

3899/10

product name :

JNJ 303

description :

Potent and selective IKs blocker

target :

Voltage-gated Potassium Channel Blockers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

440.98

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent IKs blocker (IC50 = 64 nM). Displays no effects on other cardiac channels; IC50 values are 3.3, 10, 11.1 and 12.6 M for INa, ICa, Ito and IKr currents respectively. Prolongs QT and causes unprovoked torsades de pointes (TdP).

catalog number base :

3899

product keywords :

potent Iks blockers JNJ303 potassium K+ channels selective slow delayed rectifier current KCNQ1 Kv7.1 voltage-gated voltage-dependent Voltage-Gated Potassium Channels 3899,

extended description :

Potent and selective IKs blocker

chemical name text :

2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide

formula :

C 21 H 29 ClN 2 O 4 S

formula text :

C21H29ClN2O4S

cas num :

878489-28-2

2020 USD :

185

2021 USD :

191 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage