PP 121 | Tocris Bioscience 3894 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PP 121

catalog :

3894

quantity :

25 mg

price :

382 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3894

SKU :

3894/25

product name :

PP 121

description :

Dual kinase inhibitor; inhibits PI 3-K family kinases

target :

PI 3-Kinase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

99%

observed molecular weight :

319.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dual inhibitor of receptor tyrosine kinases (RTKs) (IC50 0.02 M for Abl, Src, VEGFR-2 and PDGFR) and PI 3-K family kinases (IC50 0.06 M for p110 , DNA-PK and mTOR). Exhibits no significant effect on receptor serine/threonine kinases (RSTKs). Blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor.

catalog number base :

3894

product keywords :

PP121 PI 3-K PI 3-kinase PI3K dual inhibitors inhibits receptor tyrosine kinases RTKs PI 3-Kinase mTOR Other RTKs 3894,

extended description :

Dual kinase inhibitor; inhibits PI 3-K family kinases

chemical name text :

1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

formula :

C 17 H 17 N 7

formula text :

C17H17N7

cas num :

1092788-83-4

2020 USD :

370

2021 USD :

382 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage