NF 546 | Tocris Bioscience 3892/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NF 546

catalog :

3892/10

quantity :

10 mg

price :

264 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Su L, Bryan N, Battista S, Freitas J, Garabedian A, D Alessio F, et al. Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays. Sci Rep. 2020;10:18850 pubmed publisher
Barragán Iglesias P, Pineda Farias J, Cervantes Durán C, Bravo Hernández M, Rocha González H, Murbartián J, et al. Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells. Mol Pain. 2014;10:29 pubmed publisher
Gao Z, Wei Q, Jayasekara M, Jacobson K. The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells. Purinergic Signal. 2013;9:31-40 pubmed publisher

image

image 1 :

Cat.No. 3892 - NF 546 C47H44N6Na4O17P4 CAS No. 1006028-37-0

product information

brand :

Tocris

master code :

3892

SKU :

3892/10

rank :

0.061

product name :

NF 546

description :

Selective P2Y11 agonist

target :

P2Y Receptor Agonists

category :

Small Molecules

sizes available :

10 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NF 546 is a P2Y11 agonist (pEC50 = 6.27). Exhibits selectivity for P2Y11 over a range of P2Y and P2X receptors. Also inhibits DNA-binding activity of HMGA2 (IC50 = 5.49 M).

extended description :

Selective P2Y11 agonist

chemical name text :

4,4 -(Carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)carbonylimino))-bis(1,3-xylene-alpha,alpha -diphosphonic acid tetrasodium salt

formula :

C 47 H 44 N 6 Na 4 O 17 P 4

formula text :

C47H44N6Na4O17P4

cas num :

1006028-37-0

USD :

264 USD

product details :

Selective P2Y11 agonist

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage