PG 01037 dihydrochloride | Tocris Bioscience 3887 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PG 01037 dihydrochloride

catalog :

3887

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3887

SKU :

3887/10

product name :

PG 01037 dihydrochloride

description :

Selective D3 antagonist

target :

Dopamine D3 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

554.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dopamine D3 receptor antagonist; 133-fold selective for D3 over D2 receptors in vitro (Ki values are 0.70, 93.3 and 375 nM for D3, D2 and D4 receptors respectively). Attenuates abnormal involuntary movements associated with L-DOPA (Cat. No. 3788) in rat models of Parkinson s disease. Inhibits the effects of methamphetamine; attenuates drug-induced behaviors in vivo .

catalog number base :

3887

product keywords :

PG01037 dopamine receptors D3 antagonists dopaminergic parkinsons antiparkinsonian parkinson s D3 Receptors 3887,

extended description :

Selective D3 antagonist

chemical name text :

N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)-benzamide dihydrochloride

formula :

C 26 H 26 Cl 2 N 4 O.2HCl

formula text :

C26H26Cl2N4O.2HCl

cas num :

675599-62-9

2020 USD :

214

2021 USD :

223 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage