BIO-acetoxime | Tocris Bioscience 3874 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BIO-acetoxime

catalog :

3874

quantity :

1 mg (also 10 mg)

price :

148 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Shi Z, Lee K, Yang D, Amin S, Verma N, Li Q, et al. Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell Stem Cell. 2017;20:675-688.e6 pubmed publisher
Penas C, Mishra J, Wood S, SchÃ¼rer S, Roush W, Ayad N. GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation. Cell Cycle. 2015;14:417-24 pubmed publisher

product information

brand :

Tocris

master code :

3874

SKU :

3874/1

product name :

BIO-acetoxime

description :

Selective GSK-3 / inhibitor

target :

GSK-3 Inhibitors

category :

Small Molecules

unit size :

1 mg (also 10 mg)

purity :

98%

observed molecular weight :

398.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective GSK-3 / inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 M for GSK-3 / , CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation.

catalog number base :

3874

product keywords :

BIO-acetoxime glycogen synthase kinases 3 GSK-3 GSK3 Gsk3alpha/beta GSK3beta inhibitors inhibits selective Glycogen Synthase Kinase 3 Stem Cell Signaling Glycogen Synthase Kinase 3874,

extended description :

Selective GSK-3 / inhibitor

chemical name text :

(2 Z,3 E)-6-Bromoindirubin-3 -acetoxime

formula :

C 18 H 12 BrN 3 O 3

formula text :

C18H12BrN3O3

cas num :

667463-85-6

2020 USD :

145

2021 USD :

148 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage