BIO-acetoxime | Tocris Bioscience 3874/1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BIO-acetoxime

catalog :

3874/1

quantity :

1 mg (also 10 mg)

price :

185 USD

citations: 4

Reference
Lee K, Cho H, Rickert R, Li Q, Pulecio J, Leslie C, et al. FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation. Cell Rep. 2019;28:382-393.e7 pubmed publisher
Ellis K, Driver E, Okano T, Lemons A, Kelley M. GSK3 regulates hair cell fate in the developing mammalian cochlea. Dev Biol. 2019;: pubmed publisher
Shi Z, Lee K, Yang D, Amin S, Verma N, Li Q, et al. Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell Stem Cell. 2017;20:675-688.e6 pubmed publisher
Penas C, Mishra J, Wood S, SchÃ¼rer S, Roush W, Ayad N. GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation. Cell Cycle. 2015;14:417-24 pubmed publisher

product information

brand :

Tocris

MasterCode :

3874

SKU :

3874/1

product name :

BIO-acetoxime

target :

GSK-3 Inhibitors

category :

Small Molecules

unit size :

1 mg (also 10 mg)

purity :

98%

observed molecular weight :

398.21

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BIO-acetoxime is a selective GSK-3 / inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 M for GSK-3 / , CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation.

extended description :

Selective GSK-3 / inhibitor

chemical name text :

(2 Z,3 E)-6-Bromoindirubin-3 -acetoxime

formula :

C 18 H 12 BrN 3 O 3

formula text :

C18H12BrN3O3

cas num :

667463-85-6

USD :

185 USD

product details :

Selective GSK-3 / inhibitor

storage :

Store at +4°C