MeBIO | Tocris Bioscience 3873 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MeBIO

catalog :

3873

quantity :

10 mg

price :

169 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Volpini X, Ambrosio L, Fozzatti L, Insfrán C, Stempin C, Cervi L, et al. Trypanosoma cruzi Exploits Wnt Signaling Pathway to Promote Its Intracellular Replication in Macrophages. Front Immunol. 2018;9:859 pubmed publisher
Diamantopoulou Z, White G, Fadlullah M, Dreger M, Pickering K, Maltas J, et al. TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells. Cancer Cell. 2017;31:621-634.e6 pubmed publisher

product information

brand :

Tocris

master code :

3873

SKU :

3873/10

product name :

MeBIO

description :

Inactive analog of BIO (Cat. No. 3194)

target :

GSK-3 Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

99%

observed molecular weight :

370.2

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Control analog of 6-bromoindirubin-3 -oxime ( BIO ). Displays minimal activity against CDK1/Cyclin B, GSK-3 / , and CDK5/p25 (IC50 values are 92.0, 44-100 and 100 M respectively). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus. . Active Analog also available.

catalog number base :

3873

product keywords :

GSK-3 inhibitors inhibits control Glycogen Synthase Kinases 3 Carbohydrate Metabolism stem cells aryl hydrocarbon receptor Glycogen Synthase Kinase 3 Aryl Hydrocarbon Receptors Glycogen Synthase Kinase 3873,

extended description :

Inactive analog of BIO (Cat. No. 3194)

chemical name text :

(2 Z,3 E)-6-Bromo-1-methylindirubin-3 -oxime

formula :

C 17 H 12 BrN 3 O 2

formula text :

C17H12BrN3O2

cas num :

667463-95-8

2020 USD :

164

2021 USD :

169 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage