This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
MeBIO
catalog :
3873/10
quantity :
10 mg
price :
189 USD
citations: 3
Reference
Volpini X, Ambrosio L, Fozzatti L, Insfrán C, Stempin C, Cervi L, et al. Trypanosoma cruzi Exploits Wnt Signaling Pathway to Promote Its Intracellular Replication in Macrophages. Front Immunol. 2018;9:859 pubmed publisher
Diamantopoulou Z, White G, Fadlullah M, Dreger M, Pickering K, Maltas J, et al. TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells. Cancer Cell. 2017;31:621-634.e6 pubmed publisher
Li L, Kim H, Nellore A, Patsoukis N, Petkova V, McDonough S, et al. Prostaglandin E2 promotes survival of naive UCB T cells via the Wnt/?-catenin pathway and alters immune reconstitution after UCBT. Blood Cancer J. 2014;4:e178 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
3873
SKU :
3873/10
product name :
MeBIO
description :
Inactive analog of BIO (Cat. No. 3194)
target :
GSK-3 Inhibitors
unit size :
10 mg
category :
Small Molecules
purity :
99%
storage :
Store at +4°C
observed molecular weight :
370.2
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
MeBIO is a control analog of 6-bromoindirubin-3 -oxime ( BIO ). Displays minimal activity against CDK1/Cyclin B, GSK-3 / , and CDK5/p25 (IC50 values are 92.0, 44-100 and 100 M respectively). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus. . Active Analog also available.
product keywords :
GSK-3 inhibitors inhibits control Glycogen Synthase Kinases 3 Carbohydrate Metabolism stem cells aryl hydrocarbon receptor Glycogen Synthase Kinase 3 Aryl Hydrocarbon Receptors Glycogen Synthase Kinase 3873,
extended description :
Inactive analog of BIO (Cat. No. 3194)
chemical name text :
(2 Z,3 E)-6-Bromo-1-methylindirubin-3 -oxime
formula :
C17H12BrN3O2
formula text :
C17H12BrN3O2
cas num :
667463-95-8
USD :
210
USD 2025 :
189 USD
product details :
Inactive analog of BIO (Cat. No. 3194)
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK