(+/-)-PPCC oxalate | Tocris Bioscience 3870/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(+/-)-PPCC oxalate

catalog :

3870/10

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Rodríguez Muñoz M, Onetti Y, Cortés Montero E, Garzón J, Sánchez Blázquez P. Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor. Mol Brain. 2018;11:51 pubmed publisher
Sánchez Blázquez P, Cortés Montero E, Rodríguez Muñoz M, Garzón J. Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice. Int J Neuropsychopharmacol. 2018;21:938-948 pubmed publisher
Rodríguez Muñoz M, Sánchez Blázquez P, Garzón J. Fenfluramine diminishes NMDA receptor-mediated seizures via its mixed activity at serotonin 5HT2A and type 1 sigma receptors. Oncotarget. 2018;9:23373-23389 pubmed publisher
Malik M, Rangel Barajas C, Sumien N, Su C, Singh M, Chen Z, et al. The effects of sigma (Ïƒ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice. Br J Pharmacol. 2015;172:2519-31 pubmed publisher

image

image 1 :

Cat.No. 3870 - (?)-PPCC oxalate C24H29NO3.C2H2O4 CAS No. 932736-91-9

product information

brand :

Tocris

master code :

3870

SKU :

3870/10

rank :

0.061

product name :

(+/-)-PPCC oxalate

description :

Selective sigma ( ) agonist ( 1 2)

target :

Sigma1 Receptor Agonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

( )-PPCC oxalate is a selective sigma ( ) receptor ligand. Displays high affinity for 1; also binds at 2 sites (Ki = 1.5 nM and 50.8 nM respectively). Selective over a range of receptor types including dopaminergic and muscarinic receptors, DAT and SERT.

extended description :

Selective sigma ( ) agonist ( 1 2)

chemical name text :

(1R,2S)-rel-2-[(4-Hydroxy-4-phenyl-1-piperidinyl)methyl]-1-(4-methylphenyl)-cyclopropanecarboxylic acid methyl ester oxalate

formula :

C 24 H 29 NO 3 .C 2 H 2 O 4

formula text :

C24H29NO3.C2H2O4

cas num :

1781628-91-8

USD :

208 USD

product details :

Selective sigma ( ) agonist ( 1 2)

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage