Dexrazoxane hydrochloride | Tocris Bioscience 3857 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Dexrazoxane hydrochloride

catalog :

3857

quantity :

10 mg (also 50 mg)

price :

129 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gardner L, Malik R, Shimizu Y, Mullins N, ElShamy W. Geminin overexpression prevents the completion of topoisomerase II? chromosome decatenation, leading to aneuploidy in human mammary epithelial cells. Breast Cancer Res. 2011;13:R53 pubmed publisher

product information

brand :

Tocris

master code :

3857

SKU :

3857/10

product name :

Dexrazoxane hydrochloride

description :

Topoisomerase II inhibitor

target :

DNA Topoisomerase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

304.73

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway.

catalog number base :

3857

product keywords :

topoisomerase II inhibitors inhibits DNA isomerases ICRF187 chemotherapeutics ICRF-187 DNA, RNA and Protein Synthesis DNA Topoisomerase 3857,

extended description :

Topoisomerase II inhibitor

chemical name text :

4-[(2S)-2-(3,5-Dioxopiperazin-1-yl)propyl]piperazine-2,6-dione hydrochloride

formula :

C 11 H 16 N 4 O 4 .HCl

formula text :

C11H16N4O4.HCl

cas num :

1263283-43-7

2020 USD :

126

2021 USD :

129 USD

alt names :

ICRF-187

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage