Dexrazoxane hydrochloride | Tocris Bioscience 3857/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Dexrazoxane hydrochloride

catalog :

3857/10

quantity :

10 mg (also 50 mg)

price :

160 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gardner L, Malik R, Shimizu Y, Mullins N, ElShamy W. Geminin overexpression prevents the completion of topoisomerase II? chromosome decatenation, leading to aneuploidy in human mammary epithelial cells. Breast Cancer Res. 2011;13:R53 pubmed publisher

image

image 1 :

Cat.No. 3857 - Dexrazoxane hydrochloride C11H16N4O4.HCl CAS No. 1263283-43-7

product information

brand :

Tocris

catalog number base :

3857

SKU :

3857/10

product name :

Dexrazoxane hydrochloride

units size :

10 mg (also 50 mg)

description :

Topoisomerase II inhibitor

target :

DNA Topoisomerase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

304.73

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dexrazoxane hydrochloride is a topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway.

top caption :

Topoisomerase II inhibitor

extended description :

Topoisomerase II inhibitor

chemical name text :

4-[(2S)-2-(3,5-Dioxopiperazin-1-yl)propyl]piperazine-2,6-dione hydrochloride

formula :

C11H16N4O4.HCl

formula text :

C11H16N4O4.HCl

cas num :

1263283-43-7

USD :

160 USD

product details :

Topoisomerase II inhibitor

alt names :

ICRF-187

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage