Cyclic Pifithrin-a hydrobromide | Tocris Bioscience 3843 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cyclic Pifithrin-a hydrobromide

catalog :

3843

quantity :

10 mg (also 50 mg)

price :

184 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Benkafadar N, Menardo J, Bourien J, Nouvian R, François F, Decaudin D, et al. Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy. EMBO Mol Med. 2017;9:7-26 pubmed publisher

product information

brand :

Tocris

master code :

3843

SKU :

3843/10

product name :

Cyclic Pifithrin-a hydrobromide

description :

p53 inhibitor

target :

p53 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

349.29

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cyclic analog of pifithrin- (Cat. No. 1267), a small molecule inhibitor of p53. Prevents dexamethasone-induced cell death in murine thymocytes (EC50 = 2.01 M). Sensitizes p53-deficient tumors to radiotherapy and chemotherapy; increases apoptosis in target cells when used in combination with antimicrotubule agents.

catalog number base :

3843

product keywords :

inhibits inhibitors p53 apoptosis Cyclic Pifithrin-alpha hydrobromide Pifithrin-a Pifithrin- Pifithrin-b Pifithrin-beta Pifithrin- Pifithrin-b p53 3843,

extended description :

p53 inhibitor

chemical name text :

5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole hydrobromide

formula :

C 16 H 16 N 2 S.HBr

formula text :

C16H16N2S.HBr

cas num :

511296-88-1

2020 USD :

176

2021 USD :

184 USD

alt names :

Pifithrin-

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage