HPI 1 | Tocris Bioscience 3839 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HPI 1

catalog :

3839

quantity :

10 mg (also 50 mg)

price :

183 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3839

SKU :

3839/10

product name :

HPI 1

description :

Inhibits Hedgehog signaling

target :

Hedgehog Signaling Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

95%

observed molecular weight :

463.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4 and 6 M for Shh-, SAG-, Gli2- and Gli1-induced activation). Also inhibits Hh pathway activation in SmoM2-LIGHT cells (IC50 = 2.5 M); inhibits the proliferation of cerebellar granule neuron precursors expressing SmoM2. Does not inhibit Wnt signaling.

catalog number base :

3839

product keywords :

HPI1 Hedgehog Hh signaling signalling inhibitors inhibits Gli1 Gli2 Sonic Shh SmoM2 Hedgehog Signaling 3839,

extended description :

Inhibits Hedgehog signaling

chemical name text :

1,4,5,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-3-quinolinecarboxylic acid 2-methoxyethyl ester

formula :

C 27 H 29 NO 6

formula text :

C27H29NO6

cas num :

599150-20-6

2020 USD :

179

2021 USD :

183 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage