ER 50891 | Tocris Bioscience 3823 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ER 50891

catalog :

3823

quantity :

10 mg (also 50 mg)

price :

277 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Bi W, Liu Y, Guo J, Lin Z, Liu J, Zhou M, et al. All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity. Cell Biosci. 2018;8:48 pubmed publisher
Wang B, Fu X, Zhu M, Du M. Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation. J Mol Cell Biol. 2017;9:338-349 pubmed publisher
Li A, Figueroa S, Jiang T, Wu P, Widelitz R, Nie Q, et al. Diverse feather shape evolution enabled by coupling anisotropic signalling modules with self-organizing branching programme. Nat Commun. 2017;8:ncomms14139 pubmed publisher
MÃ¼ller P, Doliva R, Busch M, Philippeit C, Stephan H, DÃ¼nker N. Additive Effects of Retinoic Acid (RA) and Bone Morphogenetic Protein 4 (BMP-4) Apoptosis Signaling in Retinoblastoma Cell Lines. PLoS ONE. 2015;10:e0131467 pubmed publisher
Centritto F, Paroni G, Bolis M, Garattini S, Kurosaki M, Barzago M, et al. Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARÎ± expression. EMBO Mol Med. 2015;7:950-72 pubmed publisher

product information

brand :

Tocris

master code :

3823

SKU :

3823/10

product name :

ER 50891

description :

Selective RAR antagonist

target :

Retinoic Acid Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

432.51

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antagonist of RAR receptors (IC50 = 31.2 nM). Displays selective affinity for RAR (relative IC50 values are 1.8, 432 and 535 nM for RAR , RAR and RAR respectively).

catalog number base :

3823

product keywords :

ER50891 raralpha rara rar receptors antagonists retinoids retinoic acid selective Retinoic Acid Receptors 3823,

extended description :

Selective RAR antagonist

chemical name text :

4-[5-[8-(1-Methylethyl)-4-phenyl-2-quinolinyl]-1H-pyrrolo-2-benzoic acid

formula :

C 29 H 24 N 2 O 2

formula text :

C29H24N2O2

cas num :

187400-85-7

2020 USD :

266

2021 USD :

277 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage