product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
MM 11253
catalog :
3822
quantity :
10 mg (also 50 mg)
price :
219 USD
more info or order :
Tocris Bioscience product webpage
citations: 5
Reference
Bi W, Liu Y, Guo J, Lin Z, Liu J, Zhou M, et al. All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity. Cell Biosci. 2018;8:48 pubmed publisher
Metzler M, Raja S, Elliott K, Friedl R, Tran N, Brugmann S, et al. RDH10-mediated retinol metabolism and RARĪ±-mediated retinoic acid signaling are required for submandibular salivary gland initiation. Development. 2018;145: pubmed publisher
Uchibe K, Son J, Larmour C, Pacifici M, Enomoto Iwamoto M, Iwamoto M. Genetic and pharmacological inhibition of retinoic acid receptor ? function promotes endochondral bone formation. J Orthop Res. 2017;35:1096-1105 pubmed publisher
Perri M, Yap J, Yu J, Cione E, Fletcher S, KANE M. BCL-xL/MCL-1 inhibition and RARĪ³ antagonism work cooperatively in human HL60 leukemia cells. Exp Cell Res. 2014;327:183-91 pubmed publisher
Garnaas M, Cutting C, Meyers A, Kelsey P, Harris J, North T, et al. Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol. 2012;372:178-89 pubmed publisher
product information
brand :
Tocris
master code :
3822
SKU :
3822/10
product name :
MM 11253
description :
RAR -selective antagonist
target :
Retinoic Acid Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
462.67
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective RAR antagonist. Blocks the growth inhibitory ability of RAR -selective agonists in squamous cell carcinoma (SCC)-25 cells.
catalog number base :
3822
product keywords :
MM11253 retinoids retinoic acid receptors antagonists rarg rargamma rar Retinoic Acid Receptors 3822,
extended description :
RAR -selective antagonist
chemical name text :
6-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dithiolan-2-yl]-2-naphthalenecarboxylic acid
formula :
C 28 H 30 O 2 S 2
formula text :
C28H30O2S2
cas num :
345952-44-5
2020 USD :
212
2021 USD :
219 USD
storage :
Desiccate at RT
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK