MM 11253 | Tocris Bioscience 3822/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MM 11253

catalog :

3822/10

quantity :

10 mg (also 50 mg)

price :

254 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Bi W, Liu Y, Guo J, Lin Z, Liu J, Zhou M, et al. All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity. Cell Biosci. 2018;8:48 pubmed publisher
Metzler M, Raja S, Elliott K, Friedl R, Tran N, Brugmann S, et al. RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiation. Development. 2018;145: pubmed publisher
Uchibe K, Son J, Larmour C, Pacifici M, Enomoto Iwamoto M, Iwamoto M. Genetic and pharmacological inhibition of retinoic acid receptor ? function promotes endochondral bone formation. J Orthop Res. 2017;35:1096-1105 pubmed publisher
Perri M, Yap J, Yu J, Cione E, Fletcher S, KANE M. BCL-xL/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cells. Exp Cell Res. 2014;327:183-91 pubmed publisher
Garnaas M, Cutting C, Meyers A, Kelsey P, Harris J, North T, et al. Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol. 2012;372:178-89 pubmed publisher

image

image 1 :

Cat.No. 3822 - MM 11253 C28H30O2S2 CAS No. 345952-44-5

product information

brand :

Tocris

master code :

3822

SKU :

3822/10

rank :

0.061

product name :

MM 11253

description :

RAR -selective antagonist

target :

Retinoic Acid Receptor Antagonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MM 11253 is a selective RAR antagonist. Blocks the growth inhibitory ability of RAR -selective agonists in squamous cell carcinoma (SCC)-25 cells.

extended description :

RAR -selective antagonist

chemical name text :

6-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dithiolan-2-yl]-2-naphthalenecarboxylic acid

formula :

C 28 H 30 O 2 S 2

formula text :

C28H30O2S2

cas num :

345952-44-5

USD :

254 USD

product details :

RAR -selective antagonist

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage