Disulfiram | Tocris Bioscience 3807/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Disulfiram

catalog :

3807/50

quantity :

50 mg

price :

89 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Ahadome S, Abraham D, Rayapureddi S, Saw V, Saban D, Calder V, et al. Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring. JCI Insight. 2016;1:e87001 pubmed publisher
Chan C, TrinitÃ© B, Lee C, Mahajan S, Anand A, Wodarz D, et al. HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells. Retrovirology. 2016;13:1 pubmed publisher

product information

brand :

Tocris

master code :

3807

SKU :

3807/50

rank :

0.061

product name :

Disulfiram

description :

Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities

target :

Ca2+-ATPase Activators

category :

Small Molecules

sizes available :

50 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Disulfiram is an inhibitor of aldehyde dehydrogenase that displays antialcoholism activity. Shown to reversibly stimulate Ca2+-ATPase activity and inhibit V-ATPase (EC50 = 26 M). Also inhibits expression of MMP-2 and MMP-9 and displays anti-invasive activity. Pyroptosis inhibitor; binds gasdermin D (GSDMD) and inhibits pore formation. Also inhibits SARS-CoV-2 main protease (Mpro; IC50 = 9.35 M) and inhibits viral replication in Vero cells in vitro .

extended description :

Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities

chemical name text :

Bis(diethylthiocarbamyoyl)disulfide

formula :

C 10 H 20 N 2 S 4

formula text :

C10H20N2S4

cas num :

97-77-8

USD :

89 USD

product details :

Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities

alt names :

Tetraethylthiuram disulfide

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage