product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CD 2665
catalog :
3800/10
quantity :
10 mg (also 50 mg)
price :
270 USD
more info or order :
citations: 7
Reference
Chronopoulos A, Robinson B, Sarper M, Cortés E, Auernheimer V, Lachowski D, et al. ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion. Nat Commun. 2016;7:12630 pubmed publisher
Uchibe K, Son J, Larmour C, Pacifici M, Enomoto Iwamoto M, Iwamoto M. Genetic and pharmacological inhibition of retinoic acid receptor ? function promotes endochondral bone formation. J Orthop Res. 2017;35:1096-1105 pubmed publisher
Centritto F, Paroni G, Bolis M, Garattini S, Kurosaki M, Barzago M, et al. Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression. EMBO Mol Med. 2015;7:950-72 pubmed publisher
Simkin J, Zhang D, Rollo B, Newgreen D. Retinoic acid upregulates ret and induces chain migration and population expansion in vagal neural crest cells to colonise the embryonic gut. PLoS ONE. 2013;8:e64077 pubmed publisher
Martin J, Beriou G, Heslan M, Chauvin C, Utriainen L, Aumeunier A, et al. Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol. 2014;7:101-13 pubmed publisher
Liang D, Zuo A, Shao H, Born W, O Brien R, Kaplan H, et al. Retinoic acid inhibits CD25+ dendritic cell expansion and ?? T-cell activation in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2013;54:3493-503 pubmed publisher
Kang S, Park J, Cho J, Ulrich B, Kim C. Complementary roles of retinoic acid and TGF-?1 in coordinated expression of mucosal integrins by T cells. Mucosal Immunol. 2011;4:66-82 pubmed publisher
image
image 1 :
Tocris Bioscience 3800/10 image 1
Cat.No. 3800 - CD 2665 C31H34O5 CAS No. 170355-78-9
product information
brand :
Tocris
master code :
3800
SKU :
3800/10
rank :
0.061
product name :
CD 2665
description :
Selective RAR / antagonist
target :
Retinoic Acid Receptor Antagonists
category :
Small Molecules
sizes available :
10 mg (also 50 mg)
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CD 2665 is a selective RAR antagonist (KD values are 110, 306 and 1000 nM for RAR , RAR and RAR respectively). Blocks retinoic acid-induced apoptosis ex vivo .
extended description :
Selective RAR / antagonist
chemical name text :
4-[6-[(2-Methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid
formula :
C 31 H 34 O 5
formula text :
C31H34O5
cas num :
170355-78-9
USD :
270 USD
product details :
Selective RAR / antagonist
storage :
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK