Celecoxib | Tocris Bioscience 3786/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Celecoxib

catalog :

3786/10

quantity :

10 mg (also 50 mg)

price :

198 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Moser R, Annis J, Nikolova O, Whatcott C, Gurley K, Mendez E, et al. Pharmacologic Targeting of TFIIH Suppresses KRAS-Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAIL. Cancer Res. 2022;82:3375-3393 pubmed publisher
Mhillaj E, Papi M, Paciello F, Silvestrini A, Rolesi R, Palmieri V, et al. Celecoxib Exerts Neuroprotective Effects in β-Amyloid-Treated SH-SY5Y Cells Through the Regulation of Heme Oxygenase-1: Novel Insights for an Old Drug. Front Cell Dev Biol. 2020;8:561179 pubmed publisher
Bowler M, Raddatz M, Johnson C, Lindman B, Merryman W. Celecoxib Is Associated With Dystrophic Calcification and Aortic Valve Stenosis. JACC Basic Transl Sci. 2019;4:135-143 pubmed publisher
Oguh Olayinka L, Agarwal V, Ranatunge D, Campbell A, Laufer S, Cawkwell L, et al. The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma. Pathol Oncol Res. 2019;: pubmed publisher
Kim N, Lannan K, Thatcher T, Pollock S, Woeller C, Phipps R. Lipoxin B4 Enhances Human Memory B Cell Antibody Production via Upregulating Cyclooxygenase-2 Expression. J Immunol. 2018;201:3343-3351 pubmed publisher
Qiang L, Sample A, Shea C, Soltani K, Macleod K, He Y. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy. 2017;: pubmed publisher
Ohira H, Tsutsui W, Mamoto R, Yamaguchi S, Nishida M, Ito M, et al. Butyrate attenuates lipolysis in adipocytes co-cultured with macrophages through non-prostaglandin E2-mediated and prostaglandin E2-mediated pathways. Lipids Health Dis. 2016;15:213 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3786

SKU :

3786/10

product name :

Celecoxib

description :

Selective cyclooxygenase-2 (COX-2) inhibitor

target :

Cyclooxygenase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at RT

observed molecular weight :

381.37

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 M for COX-1 and COX-2 respectively). Celecoxib is an anti-inflammatory with shorter plasma half-life in vivo than SC 58121. Displays chemopreventive activity in in vivo tumor models.

product keywords :

Selective cyclooxygenase-2 COX-2 inhibitors inhibits Oxygenases Oxidases SC58635 prostaglandins SC 58635 Celebrex Cyclooxygenase 3786,

extended description :

Selective cyclooxygenase-2 (COX-2) inhibitor

chemical name text :

4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide

formula :

C17H14F3N3O2S

formula text :

C17H14F3N3O2S

cas num :

169590-42-5

USD :

192

USD 2025 :

198 USD

product details :

Selective cyclooxygenase-2 (COX-2) inhibitor

alt names :

SC 58635,Celebrex

more info or order :

Tocris Bioscience product webpage