Sildenafil citrate | Tocris Bioscience 3784/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Sildenafil citrate

catalog :

3784/5

quantity :

5 mg (also 25 mg)

price :

94 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Jiang X, MacArthur M, Treviño Villarreal J, Kip P, Ozaki C, Mitchell S, et al. Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage. Cell Chem Biol. 2021;28:1669-1678.e5 pubmed publisher
Vandendriessche B, Rogge E, Goossens V, Vandenabeele P, Stasch J, Brouckaert P, et al. The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems. PLoS ONE. 2013;8:e72155 pubmed publisher

image

image 1 :

Cat.No. 3784 - Sildenafil citrate C22H30N6O4S.C6H8O7 CAS No. 171599-83-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3784

SKU :

3784/5

product name :

Sildenafil citrate

description :

Potent PDE5 inhibitor; orally active

target :

Phosphodiesterase Inhibitors

unit size :

5 mg (also 25 mg)

category :

Small Molecules

purity :

99%

storage :

Desiccate at RT

observed molecular weight :

666.7

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Sildenafil citrate is an orally active, potent inhibitor of phosphodiesterase 5 (PDE5) (IC50 = 4 nM). Enhances nitric oxide-dependent relaxation of human corpus cavernosum in vitro . Sildenafil citrate promotes mobilization of hematopoietic stem cells (HSCs) in combination with AMD 3100 (Cat. No. 3299). Reduces pulmonary pressure and edema.

product keywords :

phosphodiesterases 5 PDE5 inhibitors inhibits orally active potent HSC hematopoietic haematopoietic stem cells mobilization COVID-19 pulmonary edema Phosphodiesterases Stem Cell Proliferation Hematopoietic Stem Cells 3784,

extended description :

Potent PDE5 inhibitor; orally active

chemical name text :

1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate

formula :

C22H30N6O4S.C6H8O7

formula text :

C22H30N6O4S.C6H8O7

cas num :

171599-83-0

USD :

USD 2025 :

94 USD

product details :

Potent PDE5 inhibitor; orally active

more info or order :

Tocris Bioscience product webpage