CP 471474 | Tocris Bioscience 3780 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CP 471474

catalog :

3780

quantity :

50 mg

price :

603 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Zariffard M, Anastos K, French A, Munyazesa E, Cohen M, Landay A, et al. Cleavage/alteration of interleukin-8 by matrix metalloproteinase-9 in the female lower genital tract. PLoS ONE. 2015;10:e0116911 pubmed publisher
Brafman D, Phung C, Kumar N, Willert K. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Cell Death Differ. 2013;20:369-81 pubmed publisher
Meierjohann S, Hufnagel A, Wende E, Kleinschmidt M, Wolf K, Friedl P, et al. MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation. Mol Cancer. 2010;9:201 pubmed publisher

product information

brand :

Tocris

master code :

3780

SKU :

3780/50

product name :

CP 471474

description :

Broad spectrum MMP inhibitor

target :

Synthetic Metalloprotease Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

97%

observed molecular weight :

368.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice.

catalog number base :

3780

product keywords :

CP471474 MMP matrix metalloproteinase metalloprotease inhibitors inhibits broad spectrum proteinases proteases Pfizer Matrix Metalloprotease 3780,

extended description :

Broad spectrum MMP inhibitor

chemical name text :

2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide

formula :

C 16 H 17 FN 2 O 5 S

formula text :

C16H17FN2O5S

cas num :

210755-45-6

2020 USD :

669

2021 USD :

603 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage