Dofetilide | Tocris Bioscience 3757 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Dofetilide

catalog :

3757

quantity :

25 mg

price :

368 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Carstensen H, Hesselkilde E, Haugaard M, Flethøj M, Carlson J, Pehrson S, et al. Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation. J Cardiovasc Electrophysiol. 2019;30:596-606 pubmed publisher
McKeithan W, Savchenko A, YU M, Cerignoli F, Bruyneel A, Price J, et al. An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. Front Physiol. 2017;8:766 pubmed publisher
Bhave G, Chauder B, Liu W, Dawson E, Kadakia R, Nguyen T, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011;79:42-50 pubmed publisher

product information

brand :

Tocris

master code :

3757

SKU :

3757/25

product name :

Dofetilide

description :

KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

target :

Voltage-gated Potassium Channel Blockers

category :

Small Molecules

unit size :

25 mg

purity :

99%

observed molecular weight :

441.56

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective potassium channel blocker. Blocks KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr). Displays class III antiarrhythmic properties.

catalog number base :

3757

product keywords :

UK68798 hERG K+ potassium channels blockers inhibits IKR delayed rectifier currents Kv voltage-gated voltage-dependent Human Ether-A-Go-Go Gene Pfizer KV11.1 Tikosyn UK 68798 Voltage-Gated Potassium Channels 3757,

extended description :

KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

chemical name text :

1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane

formula :

C 19 H 27 N 3 O 5 S 2

formula text :

C19H27N3O5S2

cas num :

115256-11-6

2020 USD :

353

2021 USD :

368 USD

alt names :

Tikosyn, UK 68798

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage