A 943931 dihydrochloride | Tocris Bioscience 3753 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

A 943931 dihydrochloride

catalog :

3753

quantity :

10 mg (also 50 mg)

price :

230 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lenz K, Pickett L, Wright C, Davis K, Joshi A, McCarthy M. Mast Cells in the Developing Brain Determine Adult Sexual Behavior. J Neurosci. 2018;38:8044-8059 pubmed publisher

product information

brand :

Tocris

master code :

3753

SKU :

3753/10

product name :

A 943931 dihydrochloride

description :

Potent and selective H4 antagonist

target :

Histamine H4 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

368.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective histamine H4 receptor antagonist (pKi values are 7.15 and 8.12 at human and rat receptors respectively). Blocks inflammation in a peritonitis mouse model and displays efficacy in inflammatory pain and neuropathic pain models.

catalog number base :

3753

product keywords :

A943931 potent selective H4 histamine 4 antagonists histaminergics receptors Histamine H4 Receptors 3753,

extended description :

Potent and selective H4 antagonist

chemical name text :

4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine

formula :

C 17 H 21 N 5 .2HCl

formula text :

C17H21N5.2HCl

cas num :

1227675-50-4

2020 USD :

225

2021 USD :

230 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage