Asenapine maleate | Tocris Bioscience 3737/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Asenapine maleate

catalog :

3737/10

quantity :

10 mg (also 50 mg)

price :

170 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gerhold K, Drdla Schutting R, Honsek S, Forsthuber L, SandkÃ¼hler J. Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J Neurosci. 2015;35:9580-94 pubmed publisher

image

image 1 :

Cat.No. 3737 - Asenapine maleate C17H16ClNO.C4H4O4 CAS No. 85650-56-2

product information

brand :

Tocris

MasterCode :

3737

SKU :

3737/10

product name :

Asenapine maleate

target :

Non-selective 5-HT Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

401.84

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Asenapine maleate is a novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8.21 for 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT6, 5-HT7, D1, D2L, D2S, D3, D4, 1A, 2A, 2B, 2C, H1 and H2 receptors respectively). Displays no appreciable affinity for muscarinic receptors. Exhibits potent activity in animal models predictive of antipsychotic efficacy.

extended description :

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

chemical name text :

(3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate

formula :

C 17 H 16 ClNO.C 4 H 4 O 4

formula text :

C17H16ClNO.C4H4O4

cas num :

85650-56-2

USD :

170 USD

product details :

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage