Indibulin | Tocris Bioscience 3728 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Indibulin

catalog :

3728

quantity :

10 mg (also 50 mg)

price :

177 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3728

SKU :

3728/10

product name :

Indibulin

description :

Microtubule destabilizer

target :

Microtubule Binding Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

389.83

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Microtubule destabilizer that blocks tubulin polymerization (IC50 = 0.3 M). Blocks cell cycle progression at metaphase and displays antitumor activity against a variety of malignancies in vitro (IC50 values ranging from 0.036 - 0.285 M). Induces complete tumor remission in the Yoshida AH13 rat sarcoma model in vivo . Lacks neurotoxicity due to an ability to discriminate between posttranslationally modified tubulin in mature neuronal microtubules and less-modified tubulin present in immature neuronal or nonneuronal microtubules. Displays oral availability and efficacy towards MDR tumor cells.

catalog number base :

3728

product keywords :

microtubule destabilizers destabilisers mitosis tubulin tau D24851 D 24851 Microtubules Mitosis 3728,

extended description :

Microtubule destabilizer

chemical name text :

2-[1-(4-Chlorobenzyl)-1H-indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide

formula :

C 22 H 16 ClN 3 O 2

formula text :

C22H16ClN3O2

cas num :

204205-90-3

2020 USD :

173

2021 USD :

177 USD

alt names :

D 24851

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage