PD 161570 | Tocris Bioscience 3724/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PD 161570

catalog :

3724/10

quantity :

10 mg (also 50 mg)

price :

336 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Suzuki A, Sugiyama G, Ohyama Y, Kumamaru W, Yamada T, Mori Y. Regulation of NF-kB Signalling Through the PR55β-RelA Interaction in Osteoblasts. In Vivo. 2020;34:601-608 pubmed publisher
Valdez Magaña G, Rodriguez A, Zhang H, Webb R, Alberio R. Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation. Dev Biol. 2014;387:15-27 pubmed publisher
Rodriguez A, Allegrucci C, Alberio R. Modulation of pluripotency in the porcine embryo and iPS cells. PLoS ONE. 2012;7:e49079 pubmed publisher

image

image 1 :

Cat.No. 3724 - PD 161570 C26H35Cl2N7O CAS No. 192705-80-9

product information

brand :

Tocris

MasterCode :

3724

SKU :

3724/10

product name :

PD 161570

target :

FGF Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

532.51

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PD 161570 is a selective FGFR inhibitor (IC50 values are 40, 262 and 3700 nM for FGFR, PDGFR and EGFR respectively). Inhibits FGFR receptor phosphorylation (IC50 = 622 nM) and growth of A121 cells in vitro .

extended description :

Selective FGFR inhibitor

chemical name text :

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N -(1,1-dimethylethyl)urea

formula :

C 26 H 35 Cl 2 N 7 O

formula text :

C26H35Cl2N7O

cas num :

192705-80-9

USD :

336 USD

product details :

Selective FGFR inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage